课题案例:lncRNA通过A信号调节细胞X表型转化

(A) Expression of protein A in X cells.
(B) Phenotype modulation of X cells. Increase of protein A could promote cell proliferation and migration by transferring over- expression plasmid into X cells. * 0.01 < p < 0.5; n=3, mean±SD.

(A) Expression of protein A in X cells.
(B) Phenotype modulation of X cells.
(C) Mechanism of signal pathway. Contrary to overexpression of A, knock-down by siRNA and interrupt protein A activating by inhibitor could block phenotype modulation in X cells through relative signals. * 0.01 < p < 0.5; ** p < 0.001; n=3, mean±SD..

(A) Expression of protein A in X cells.
(B) Phenotype modulation of X cells.
(C) Mechanism of signal pathway. The lncRNA mimic could enhance the ability of cell proliferation and migration by up-regulating A and relative signals in X cells, which lncRNA inhibitor down-regulated. * 0.01 < p < 0.5; ** p < 0.001; n=3, mean±SD.
